BDBM163619 UF010::US10807944, Compound UF010::US11731934, Compound UF010
SMILES CCCCNNC(=O)c1ccc(Br)cc1
InChI Key InChIKey=BVQCFCYPFJOOAV-UHFFFAOYSA-N
Data 47 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 163619
Affinity DataIC50: 9.10E+3nMpH: 8.0Assay Description:Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...More data for this Ligand-Target Pair
Affinity DataIC50: 9.09E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.10E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using p53 (379 to 382 residues) (Arg-His-Lys(Ac)-Lys(Ac)) as substrate by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of recombinant human HDAC6 using fluorescent as substrate measured for 10 mins by fluorescence based microtiter plate assayMore data for this Ligand-Target Pair